prostate-specific antigen

noun

pros·​tate-spe·​cif·​ic antigen
: a protease secreted by epithelial cells of the prostate gland that is used in the diagnosis of prostate cancer since its concentration in blood serum tends to be proportional to the clinical stage of the disease
abbreviation PSA

Examples of prostate-specific antigen in a Sentence

Recent Examples on the Web Though blood tests known as prostate-specific antigen (PSA) tests are now the standard for screening, many men still associate prostate cancer exams with rectal exams. Robin Cole, Fortune, 12 Apr. 2024 What the color of urine tells you about your health What is prostate-specific antigen testing? Dr. Jamin Brahmbhatt, CNN, 4 Mar. 2024 Prostate cancer is a good example of this, Stein explained—what appears to be a spike in prostate cancer cases in the 1990s and 2000s was simply an increase in more widespread prostate-specific antigen (PSA) testing. Julia Landwehr, Health, 30 Jan. 2024 In Britain, men over 50 do not routinely undergo prostate-specific antigen (PSA) tests to screen for prostate cancer, as is common in the United States. William Booth, Washington Post, 17 Jan. 2024 It is recommended that men 55 to 69 receive a prostate-specific antigen, or PSA, blood test and a rectal exam annually, Gburek said. Daniel Gonzalez, The Arizona Republic, 14 Jan. 2024 The blood and prostate-specific antigen tests are acceptable as long as they are done in the same hospital or lab. Dominique Fluker, Essence, 8 Feb. 2024 Some physicians and organizations have discouraged screening with the prostate-specific antigen (PSA) blood test, citing the lack of a survival benefit from screening and the risk of overtreatment, Showalter noted. Melissa Rudy, Fox News, 22 Jan. 2024 Right now, the main way to get screened is to have a blood sample tested for prostate-specific antigen (PSA) markers. Rayna Reid Rayford, Essence, 9 Sep. 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'prostate-specific antigen.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1979, in the meaning defined above

Time Traveler
The first known use of prostate-specific antigen was in 1979

Dictionary Entries Near prostate-specific antigen

Cite this Entry

“Prostate-specific antigen.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prostate-specific%20antigen. Accessed 27 Apr. 2024.

Medical Definition

prostate-specific antigen

noun
: a protease that is secreted by the epithelial cells of the prostate and is used in the diagnosis of prostate cancer since its concentration in the blood serum tends to be proportional to the clinical stage of the disease
abbreviation PSA

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